发明名称 NEW APOPTOSIS-INDUCING AGENT
摘要 PROBLEM TO BE SOLVED: To provide a new and easy to synthesize apoptosis-inducing agent exhibiting the apoptosis-inducing activity against various cancer cell lines in a lower concentration and also exhibiting cytotoxicity in the lower concentration. SOLUTION: This apoptosis-inducing agent has a 2 ring core structure expressed by the following general formula (1) as a base skeleton, and consists of e.g. a synthetic intermediate, etc., of halichlorine which is a kind of a natural product having a cell adhesion-controlling activity. COPYRIGHT: (C)2003,JPO
申请公布号 JP2003171278(A) 申请公布日期 2003.06.17
申请号 JP20010372050 申请日期 2001.12.05
申请人 JAPAN SCIENCE & TECHNOLOGY CORP 发明人 ITO KOJI;SHISHIDO KOZO;SHINDO MITSURU
分类号 C07D455/00;A61K31/438;A61K31/695;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07D498/04;C07F7/18;(IPC1-7):A61K31/438 主分类号 C07D455/00
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