发明名称 |
Bezamide derivatives for the treatment of diseases mediated by cytokines |
摘要 |
The invention concerns the use of amide derivatives of formula (I) wherein: R1 and R2 are substituents such as hydroxy, C1-6alkoxy, mercapto, C1-6alkylthio, amino, C1-6alkylamino and di-(C1-6alkyl)amino; m and p are independently 0-3; R3 is C1-4alkyl; q is 0-4; and R4 is aryl or cycloalkyl; or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in the treatment of diseases or medical conditions mediated by cytokines.
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申请公布号 |
US6579872(B1) |
申请公布日期 |
2003.06.17 |
申请号 |
US20000674560 |
申请日期 |
2000.11.02 |
申请人 |
ASTRAZENECA AB |
发明人 |
BROWN DEARG S;BROWN GEORGE R |
分类号 |
C07D295/10;A61K31/165;A61K31/167;A61K31/18;A61K31/216;A61K31/22;A61K31/275;A61K31/40;A61K31/4164;A61K31/4402;A61K31/445;A61K31/4453;A61K31/454;A61K31/495;A61K31/5375;A61K31/5377;A61K31/55;A61P1/04;A61P9/02;A61P9/04;A61P11/06;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P31/18;A61P37/00;A61P43/00;C07C235/56;C07C237/40;C07C255/57;C07C311/08;C07D207/08;C07D207/12;C07D207/20;C07D211/22;C07D211/46;C07D213/30;C07D223/08;C07D233/60;C07D239/34;C07D277/24;C07D295/092;C07D295/13;C07D295/14;C07D295/155;C07D303/22;C07D307/20;C07D521/00;(IPC1-7):A61K31/535;C07D413/02 |
主分类号 |
C07D295/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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