发明名称 |
Method for producing fibronectin and fibrinogen compositions using a polyalkylene glycol and glycine or beta-alanine |
摘要 |
A method of producing a pharmaceutical preparation comprising fibronectin and fibrinogen is disclosed. The method involves admixing into a starting solution of fibrinogen and fibronectin, in a single step, a precipitating composition comprising a polyalkylene glycol and at least one of glycine and beta-alanine which forms a precipitate. Next, the precipitate is collected and a pharmaceutical preparation is prepared from the precipitate. The pharmaceutical preparation has a fibronectin:fibrinogen ratio from about 0.02 to about 0.2.
|
申请公布号 |
US6579537(B2) |
申请公布日期 |
2003.06.17 |
申请号 |
US20000502029 |
申请日期 |
2000.02.10 |
申请人 |
BAXTER AKTIENGESELLSCHAFT |
发明人 |
SEELICH THOMAS;BROERMANN RALF |
分类号 |
A61L24/00;A61L15/64;A61L24/10;A61L26/00;A61L27/22;C07K1/30;C07K14/75;C07K14/755;C07K14/78;(IPC1-7):A61K35/16;A61K38/48;C12N9/48 |
主分类号 |
A61L24/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|