发明名称 AMINOTETRALIN DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS
摘要 This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, or individual isomers, racemic or non-racemic mixtures of isomers, or acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, processes for their preparation and their use as therapeutic agents.
申请公布号 CA2469055(A1) 申请公布日期 2003.06.12
申请号 CA20022469055 申请日期 2002.11.25
申请人 F. HOFFMANN-LA ROCHE AG 发明人 MADERA, ANN MARIE;WEIKERT, ROBERT JAMES
分类号 A61K31/4545;A61K31/496;A61K31/5377;A61K31/551;A61P1/00;A61P11/00;A61P13/02;A61P13/10;A61P43/00;C07D211/58;C07D211/60;C07D211/62;C07D401/06;C07D401/10;C07D405/06;C07D409/12;C07D413/06;C07D413/12;(IPC1-7):C07D211/58;A61K31/445;A61K31/495;A61K31/535;A61K31/55 主分类号 A61K31/4545
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