发明名称 |
AMINOTETRALIN DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS |
摘要 |
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, or individual isomers, racemic or non-racemic mixtures of isomers, or acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, processes for their preparation and their use as therapeutic agents.
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申请公布号 |
CA2469055(A1) |
申请公布日期 |
2003.06.12 |
申请号 |
CA20022469055 |
申请日期 |
2002.11.25 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
MADERA, ANN MARIE;WEIKERT, ROBERT JAMES |
分类号 |
A61K31/4545;A61K31/496;A61K31/5377;A61K31/551;A61P1/00;A61P11/00;A61P13/02;A61P13/10;A61P43/00;C07D211/58;C07D211/60;C07D211/62;C07D401/06;C07D401/10;C07D405/06;C07D409/12;C07D413/06;C07D413/12;(IPC1-7):C07D211/58;A61K31/445;A61K31/495;A61K31/535;A61K31/55 |
主分类号 |
A61K31/4545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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