TRIAZOLE COMPOUND AND MEDICINAL USE THEREOF

摘要

A sodium−phosphate cotransporter inhibitor which contains as an active ingredient a triazole compound represented by the general formula (1): (1) (wherein R1, R2, and R3 are the same or different and each is hydrogen, C1−6 haloalkyl, halogeno, nitro, amino, cyano, C1−7 alkyl, C1−6 alkoxy, etc.; R4 is C1−6 haloalkyl, C1−7 alkyl, etc.; R5, R6, R7, and R8 are the same or different and each is hydrogen, halogeno, C1−6 haloalkyl, C1−7 alkyl, C1−6 alkoxy, or nitro; and ring A is aryl or an aromatic heterocyclic group), a prodrug thereof, or a pharmaceutically acceptable salt of any of these. The inhibitor is useful as a therapeutic agent for hyperphosphemia which has sodium−phosphate cotransporter inhibitory activity.