| 发明名称 |
METHOD FOR TREATING OCULAR HYPERTENSION |
| 摘要 |
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions that are related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
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| 申请公布号 |
CA2466757(A1) |
申请公布日期 |
2003.06.12 |
| 申请号 |
CA20022466757 |
申请日期 |
2002.11.27 |
| 申请人 |
MERCK & CO., INC.;MERCK FROSST CANADA & CO. |
发明人 |
METTERS, KATHLEEN MARY;OGIDIGBEN, MILLER J.;YOUNG, ROBERT N.;SLIPETZ, DEBORAH M.;BILLOT, XAVIER |
| 分类号 |
C07D403/06;A61K9/00;A61K31/4015;A61K31/41;A61K31/557;A61K31/5575;A61K31/559;A61K45/06;A61P27/00;A61P27/06;C07D207/27;(IPC1-7):A61K31/41;A61K31/122;A61K31/401;A61K31/402 |
主分类号 |
C07D403/06 |
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