发明名称 |
Maytansines and maytansine conjugates |
摘要 |
Cytotoxin-targeting molecule conjugates comprising cytotoxin and an antibody, growth factor, or polysaccharide together with a pH-sensitive or redox potential-sensitive linker. Novel ansamitocins and recombinant genes and organisms that produce them. The use of the described conjugates in the treatment of cancer and other hyperproliferation diseases.
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申请公布号 |
US2003109682(A1) |
申请公布日期 |
2003.06.12 |
申请号 |
US20020235228 |
申请日期 |
2002.09.03 |
申请人 |
SANTI DANIEL;MYLES DAVID C.;METCALF BRIAN;HUTCHINSON C. RICHARD;ASHLEY GARY |
发明人 |
SANTI DANIEL;MYLES DAVID C.;METCALF BRIAN;HUTCHINSON C. RICHARD;ASHLEY GARY |
分类号 |
A61K47/48;(IPC1-7):C07K16/46 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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