| 发明名称 |
EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF |
| 摘要 |
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modelin g and remodeling processes of the osteoblasts and osteoclasts.
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| 申请公布号 |
CA2466751(A1) |
申请公布日期 |
2003.06.12 |
| 申请号 |
CA20022466751 |
申请日期 |
2002.11.27 |
| 申请人 |
MERCK AND CO., INC.;MERCK FROSST CANADA & CO. |
发明人 |
OGIDIGBEN, MILLER J.;SLIPETZ, DEBORAH M.;METTERS, KATHLEEN M.;YOUNG, ROBERT N.;BILLOT, XAVIER |
| 分类号 |
A61K31/4015;A61K31/4025;A61K31/41;A61P1/02;A61P3/14;A61P19/02;A61P19/08;A61P19/10;A61P27/02;A61P27/06;A61P35/00;A61P43/00;C07D207/24;C07D207/26;C07D403/12;(IPC1-7):C07D403/12;A61K31/401 |
主分类号 |
A61K31/4015 |
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