| 发明名称 |
Methods for identification of agents which modulate chloride channel activity |
| 摘要 |
A new gene in the calcium-activated chloride channel family has been discovered that is induced by L-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered.
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| 申请公布号 |
US6576434(B1) |
申请公布日期 |
2003.06.10 |
| 申请号 |
US20010623624 |
申请日期 |
2001.02.13 |
| 申请人 |
GENAERA CORPORATION |
发明人 |
HOLROYD KENNETH J.;LEVITT ROY C.;MALOY W. LEE;LOUAHED JAMILA;MCLANE MIKE;NICOLAIDES NICHOLAS C.;ZHOU YUHONG;DONG QU |
| 分类号 |
G01N33/53;A61K31/7088;A61K38/00;A61K38/20;A61K39/395;A61K45/00;A61P1/00;A61P11/00;A61P11/06;A61P37/08;A61P43/00;C07H21/04;C07K14/705;C12N15/09;C12N15/12;C12P21/08;G01N33/68;(IPC1-7):G01N33/53;G01N33/567 |
主分类号 |
G01N33/53 |
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