发明名称 |
Pharmaceutical compositions, dosage forms and methods for oral administration of epothilones |
摘要 |
The invention relates to methods of increasing the bioavailability of orally administered epothilones. Epothilones administered by the methods of the invention are sufficiently bioavailable to have a pharmacological effect The invention further relates to pharmaceutical compositions, pharmaceutical dosage forms, and kits for use in the methods of the invention.
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申请公布号 |
US6576651(B2) |
申请公布日期 |
2003.06.10 |
申请号 |
US20020057390 |
申请日期 |
2002.01.25 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BANDYOPADHYAY REBANTA;MALLOY TIMOTHY M.;PANAGGIO ANDREA;RAGHAVAN KRISHNASWAMY SRINIVAS;VARIA SAILESH AMILAL |
分类号 |
C07D491/044;A61K9/00;A61K9/08;A61K9/10;A61K9/28;A61K31/425;A61K31/427;A61K47/02;A61K47/10;A61K47/12;A61K47/44;A61P35/00;A61P43/00;C07D493/04;(IPC1-7):A61K31/425 |
主分类号 |
C07D491/044 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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