发明名称 BIPHENYL DERIVATIVES AND THE USE THEREOF AS INTEGRIN INHIBITORS.
摘要 <p>The invention relates to novel biphenyl derivatives of the general formula (I), wherein R<4 >represents an aromatic heterocycle, and to the physiologically acceptable salts or solvates thereof. The inventive compounds are integrin inhibitors and are used for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections and restenosis following angioplasty or for pathological processes that are maintained or propagated by angiogenesis.</p>
申请公布号 MXPA03001557(A) 申请公布日期 2003.06.06
申请号 MX2003PA01557 申请日期 2001.08.02
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 GOODMAN, SIMON
分类号 A61K31/4168;A61K31/4184;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P17/02;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P41/00;A61P43/00;C07D233/48;C07D233/88;C07D235/30;(IPC1-7):A61K31/416 主分类号 A61K31/4168
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