The present invention relates to a new process for the preparation of the (S)-naproxen 4-nitrooxybutyl ester and to new intermediates obtained and used therein. The invention further relates to the use of the new intermediates for the manufacturing of pharmaceutically active compounds such as (S)-naproxen 4-nitrooxybutyl ester.The invention also relates to the use of (S)-naproxen 4-nitrooxybutyl ester prepared according to the process of the present invention for the manufacturing of a medicament for the treatment of pain.
申请公布号
WO03045896(A1)
申请公布日期
2003.06.05
申请号
WO2002SE02184
申请日期
2002.11.26
申请人
ASTRAZENECA AB;BELLI, ALDO;CANNATA, VINCENZO;FONDUCA, TELLY;HEDBERG, MARTIN;WESTERMARK, ANDREAS;VILLA, MARCO
发明人
BELLI, ALDO;CANNATA, VINCENZO;FONDUCA, TELLY;HEDBERG, MARTIN;WESTERMARK, ANDREAS;VILLA, MARCO