发明名称 NEW PROCESS
摘要 The present invention relates to a new process for the preparation of the (S)-naproxen 4-nitrooxybutyl ester and to new intermediates obtained and used therein. The invention further relates to the use of the new intermediates for the manufacturing of pharmaceutically active compounds such as (S)-naproxen 4-nitrooxybutyl ester.The invention also relates to the use of (S)-naproxen 4-nitrooxybutyl ester prepared according to the process of the present invention for the manufacturing of a medicament for the treatment of pain.
申请公布号 WO03045896(A1) 申请公布日期 2003.06.05
申请号 WO2002SE02184 申请日期 2002.11.26
申请人 ASTRAZENECA AB;BELLI, ALDO;CANNATA, VINCENZO;FONDUCA, TELLY;HEDBERG, MARTIN;WESTERMARK, ANDREAS;VILLA, MARCO 发明人 BELLI, ALDO;CANNATA, VINCENZO;FONDUCA, TELLY;HEDBERG, MARTIN;WESTERMARK, ANDREAS;VILLA, MARCO
分类号 A61K31/21;A61K31/216;A61P29/00;C07B61/00;C07C67/08;C07C67/58;C07C201/02;C07C203/04;C07C301/00;C07C303/28;C07C309/66;C07C309/67;C07C309/73 主分类号 A61K31/21
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