| 发明名称 |
Methods and compositions for lowering the level of tumor necrosis factor (TNF) in TNF-associated disorders |
| 摘要 |
The present invention provides recombinant adeno-associated virus (rAAV) vectors encoding a tumor necrosis factor (TNF) antagonist and methods using these vectors to reduce levels of TNF in a mammal. The invention also provides methods of using these rAAV vectors in palliating TNF-associated disorders.
|
| 申请公布号 |
US2003103942(A1) |
申请公布日期 |
2003.06.05 |
| 申请号 |
US20020313852 |
申请日期 |
2002.12.06 |
| 申请人 |
BURSTEIN HAIM;STEPAN ANTHONY M. |
发明人 |
BURSTEIN HAIM;STEPAN ANTHONY M. |
| 分类号 |
C12N15/09;A61K35/76;A61K45/00;A61K48/00;A61P19/02;A61P29/00;C07K14/715;C12N5/10;C12N7/00;C12N15/12;C12N15/864;(IPC1-7):A61K48/00;C12N15/861 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
