发明名称 CONTRAST AGENTS FOR THE IN VIVO DETECTION OF ENZYME ACTIVITY
摘要 The invention relates to a method for the detection of enzyme activity in vivo by means of determination of fluorine chemical shift with 19F-MRI or 19F-NMR, using enzyme substrates containing at least one fluorine atom as contrast agents or NMR markers.
申请公布号 WO03045441(A1) 申请公布日期 2003.06.05
申请号 WO2002NO00452 申请日期 2002.11.28
申请人 AMERSHAM HEALTH AS;KLAVENESS, JO;RONGVED, PAAL;TOLLESHAUG, HELGE 发明人 KLAVENESS, JO;RONGVED, PAAL;TOLLESHAUG, HELGE
分类号 A61K49/06;G01N33/573;G01N33/58;G01R33/465;(IPC1-7):A61K49/06;A61B5/055;C12Q1/00;G01N24/00 主分类号 A61K49/06
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