CONTRAST AGENTS FOR THE IN VIVO DETECTION OF ENZYME ACTIVITY
摘要
The invention relates to a method for the detection of enzyme activity in vivo by means of determination of fluorine chemical shift with 19F-MRI or 19F-NMR, using enzyme substrates containing at least one fluorine atom as contrast agents or NMR markers.
申请公布号
WO03045441(A1)
申请公布日期
2003.06.05
申请号
WO2002NO00452
申请日期
2002.11.28
申请人
AMERSHAM HEALTH AS;KLAVENESS, JO;RONGVED, PAAL;TOLLESHAUG, HELGE