发明名称 PYRAZOLOPYRIDINE DERIVATIVES
摘要 Compounds of formula (I), or a salt thereof, or a solvate thereof, wherein, R <sp>1</sp> is halo, -N=N-heteroaryl, -CO<sb>2</sb>R<sp>5</sp>, -NHCH<sb>2</sb>R<sp>6</sp>; or -CONR<sp>7</sp>R<sp>8</sp>; R<sp>2</sp> is H or aryl; R<sp>3</sp> is H or aryl, wherein the aryl ring may be optionally substituted by one or more substituents, which may be the same or different, selected from halo; R<sp>4</sp> is H; R<sp>5</sp> is alkyl; and R<sp>6</sp> is H, alkyl, cycloalkyl, aryl or aralkyl; R<sp>7</sp> and R<sp>8</sp> are selected from H and alkyl; and with the proviso that when R<sp>1</sp> is halo, at least one of R<sp>2</sp> and/or R<sp>3</sp> is aryl; a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds and composition in medicine.
申请公布号 WO03045949(A1) 申请公布日期 2003.06.05
申请号 WO2002EP13261 申请日期 2002.11.25
申请人 SMITHKLINE BEECHAM P.L.C.;HAIGH, DAVID;HICKEY, DEIRDRE, MARY, BERNADETTE;LIDDLE, JOHN;SLINGSBY, BRIAN, PETER;WARD, ROBERT, WILLIAM;WITHERINGTON, JASON 发明人 HAIGH, DAVID;HICKEY, DEIRDRE, MARY, BERNADETTE;LIDDLE, JOHN;SLINGSBY, BRIAN, PETER;WARD, ROBERT, WILLIAM;WITHERINGTON, JASON
分类号 A61P9/00;A61P25/00;C07D471/04;(IPC1-7):C07D471/04;A61K31/437 主分类号 A61P9/00
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