发明名称 |
SELF-ASSEMBLY MOLECULES |
摘要 |
<p>There is provided a method of forming a multimeric complex having affinity f or a target. The method comprises: obtaining a plurality of self-assembly molecules, said self-assembly molecules including complementary self-assembl y units such as verotoxin subunit B, each of which is operatively connected to an interaction domain such as a single domain antibody specific for the target; and combining said self-assembly molecules such that at least three said self-assembly units simultaneously bind to one another so as to permit the single domain antibodies to bind the target.</p> |
申请公布号 |
CA2468583(A1) |
申请公布日期 |
2003.06.05 |
申请号 |
CA20022468583 |
申请日期 |
2002.11.29 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
ZHANG, JIANBING;MACKENZIE, C. ROGER |
分类号 |
G01N33/566;A61K38/00;A61K39/395;A61P31/12;A61P35/00;A61P43/00;C07K14/235;C07K14/245;C07K16/00;C07K16/26;C07K19/00;G01N33/569;G01N33/574;(IPC1-7):C07K19/00;C07K16/18;C07K16/46;G01N33/53;C07K14/705 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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