摘要 |
<p>Methods and kits are provided for diagnosing medical conditions of patients with a disease or condition characterized by endothelial dysfunction based on a nitric oxide bioactivity index. Nitric oxide bioactivity index is the ratio of the level of a nitric oxide-related product such as nitrate or nitrite to the level of an oxidant stress-related product such as isoprostane in plasma, urine, or another specimen from a patient. Methods are also provided for using the nitric oxide bioactivity index to treat patients with endothelial dysfunction and monitor the course of treatment.</p> |