| 发明名称 |
Enzymatic assays for screening anti-cancer agents |
| 摘要 |
Methods of identifying anti-cancer agents are provided based on ligand binding or enzymatic activity of TIP49 family members. The assays may include the measurement of ATPase and/or helicase activity. Also provided are anti-cancer agents identified by the screening methods of the invention, as well as the use of the agent for the prophylaxis or treatment of cancer. A complex of a TIP49 family member with various proteins that regulate transcription is also provided.
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| 申请公布号 |
US2003104500(A1) |
申请公布日期 |
2003.06.05 |
| 申请号 |
US20020276015 |
申请日期 |
2002.11.12 |
| 申请人 |
GSTAIGER MATTHIAS GEORG CHRISTIAN;KREK WILHELM |
发明人 |
GSTAIGER MATTHIAS GEORG CHRISTIAN;KREK WILHELM |
| 分类号 |
G01N33/50;A61K31/7088;A61K31/7105;A61K31/711;A61K31/7125;A61K35/12;A61K35/64;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P1/16;A61P3/10;A61P7/00;A61P9/00;A61P11/00;A61P13/12;A61P17/02;A61P21/00;A61P25/00;A61P31/04;A61P31/18;A61P35/00;A61P37/00;A61P43/00;C07K14/47;C07K14/82;C07K16/18;C07K16/32;C07K19/00;C12N1/15;C12N1/19;C12N5/10;C12N9/00;C12N9/16;C12N15/09;C12P21/08;C12Q1/02;C12Q1/25;C12Q1/34;G01N33/15;G01N33/53;G01N33/566;G01N33/574;(IPC1-7):G01N33/574;A61K38/17 |
主分类号 |
G01N33/50 |
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