SYSTEM AND METHOD FOR DETERMINING RADIUS OF GYRATION, MOLECULAR WEIGHT, AND INTRINSIC VISCOSITY OF A POLYMERIC DISTRIBUTION USING GEL PERMEATION CHROMATOGRAPHY AND LIGHT-SCATTERING DETECTION

摘要

A system and method for analyzing data from a gel permeation chromatography (GPC) or size exclusion chromatography (SEC) system for determining a polymeric sample's radius of gyration. Data from two or more detectors (18) is used with a least-squares minimization fit (20). A novel method includes the simultaneous determination of a sample's radius of gyration using data from a light scattering detector that collects data from at least two incident angles. Detectors within the inventive method include a multi-angle light scattering (LS) detector, viscometer (V) and a refractive index (RI) detector.