发明名称 BICYCLIC DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE
摘要 A heterocyclic compound represented by the general formula (V) (wherein R<sp>1b</sp> represents substituted C<sb>6-10</sb> aryl, etc.; T<sp>a</sp> represents a single bond, C<sb>1-6</sb> alkyl, -CH<sb>2</sb>O-, etc.; X and Y are the same or different and each represents optionally substituted nitrogen, etc.; the broken lines each indicates a single bond or double bond; Z<sp>a</sp> represents nitrogen or CH; W represents a single bond, oxygen, etc.; and Q represents an optionally substituted C<sb>6-10</sb> aryl or optionally substituted aromatic heterocyclic group) or a salt of the compound. The compound and salt have excellent tyrosin kinase inhibitory activity. Also provided is a medicinal composition containing the heterocyclic compound or salt.
申请公布号 WO03045929(A1) 申请公布日期 2003.06.05
申请号 WO2002JP12264 申请日期 2002.11.25
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD.;ODA, TSUNEO;IMADA, TAKASHI;NAITO, KENICHIRO;TAMURA, TOSHIYA;FURUYA, SHUICHI 发明人 ODA, TSUNEO;IMADA, TAKASHI;NAITO, KENICHIRO;TAMURA, TOSHIYA;FURUYA, SHUICHI
分类号 A61K31/423;A61K31/437;A61K31/5377;A61P35/00;A61P43/00;C07D235/10;C07D263/56;C07D263/57;C07D413/04;C07D413/12;C07D413/14;C07D471/04;(IPC1-7):C07D263/56;A61K38/05;A61K31/537 主分类号 A61K31/423
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