| 发明名称 |
5-HYDROXYTRYPTAMINE RECEPTOR GENE POLYMORPHISMS AND RESPONSE TO TREATMENT |
| 摘要 |
Correlations between polymorphisms in the 5-hydroxytryptamine 3 receptor gene, and/or polymorphisms in the UGT1A4 gene, and a subject's phenotypic response to treatment with 5-hydroxytryptamine ligands are described. Methods of screening subjects to aid in treatment, methods of screening 5HT ligands, and methods of treatment are presented. |
| 申请公布号 |
EP1315837(A2) |
申请公布日期 |
2003.06.04 |
| 申请号 |
EP20010968309 |
申请日期 |
2001.08.31 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
DAVIS, KOURTNEY, J;FLING, MARY, E;HUGHES, ARLENE, R;MANASCO, PENELOPE, K;STUBBINS, MICHAEL, J |
| 分类号 |
G01N33/50;A61K31/4178;A61K31/437;A61K31/439;A61K45/00;A61P1/00;A61P1/10;A61P1/12;A61P43/00;C12N15/09;C12Q1/68;G01N33/15;(IPC1-7):C12Q1/68;A61K31/415;C07K14/705 |
主分类号 |
G01N33/50 |
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