| 摘要 |
A novel process is proposed for the preparation of 1,3-disubstituted 2- nitroguanidines of the formula I (See Formula I) in which R1 is hydrogen or C1-C4alkyl, R2 is hydrogen, C1-C6alkyl; C3- C6cycloalkyl or a radical -CH2B; A is an unsubstituted or mono- to tetrasubstituted aromatic o r non-aromatic, monocyclic or bicyclic heterocyclic radical, which may contain one or two substituents from the group comprising C1-C3haloalkyl having 1 to 7 halogen atoms, cyclopropyl, halocyclopropyl having 1 to 3 halogen atoms, C2-C3alkenyl, C2- C3alkynyl, C2-C3haloalkenyl and C2-C3haloalkynyl having 1 to 4 halogen atoms, C1- C3haloalkoxy having 1 to 7 halogen atoms C1-C3alkylthio, C1-C3haloalkylthio having 1 to 7 halogen atoms; allyloxy, propargyloxy, allylthio, propargylthio, haloallyloxy; haloallylthio, cyano and nitro and one to four substituents from the group comprising C1-C3alkyl, C1-C3alkoxy and halogen; and B is phenyl, cyanophenyl, nitrophenyl, halophenyl having 1 to 3 halogen atoms, phenyl substituted by C1-C3alkyl, C1-C3haloalkyl having 1 to 7 haloge n atoms, C1-C3alkoxy or C1-C3haloalkoxy having 1 to 7 halogen atoms, 3-pyridyl, 5- thiazolyl, 5-thiazolyl substituted by one or two substituents from the group comprising C1-C3alkyl, C1-C3haloalkyl having 1 to 7 halogen atoms, cyclopropyl, halocyclopropyl, C2 - C3alkenyl, C2-C3alkynyl, C1-C3alkoxy, C2-C3haloalkenyl and C2-C3haloalkynyl having 1 to 4 halogen atoms, C1-C3haloalkoxy having 1 to 7 halogen atoms, C1-C3alkylthio, C1-C3haloalkylthio having 1 to 7 halogen atoms, allyloxy, propargyloxy, allylthio, propargylthio, haloallyloxy, haloallylthio, halogen, cyano and nitro, or 3- pyridyl substituted by one or two radicals from the group comprising C1-C3haloalkyl having 1 to 7 halogen atoms, cyclopropyl, halocyclopropyl, C2-C3alkenyl, C2-C3alkynyl, C2-C3haloalkenyl and C2-C3haloalkynyl having 1 to 4 halogen atoms, C1- C3haloalkoxy having 1 to 7 halogen atoms, C1-C3alkylthio, C1-C3haloalkylthio having 1 to 7 halogen atoms, allyloxy, propargyloxy, allylthio, propargylthio, haloallyloxy, haloallylthio, cyano and nitro or by one to four radicals from the group comprising C1-C3alkyl, C 1- C3alkoxy and halogen, which comprises hydrolysing a compound of the formula II (See Formula II) in which R3 is unsubstituted or substituted C1-C10alkyl, C3-C6cycloalkyl, phenyl or benzyl. The compounds of the formula I are suitable as intermediates for the preparation of pesticides.
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