PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF
摘要
The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.
申请公布号
WO03043979(A2)
申请公布日期
2003.05.30
申请号
WO2002US37155
申请日期
2002.11.19
申请人
DANA FARBER CANCER INSTITUTE;ROSOWSKY, ANDRE;FORSCH, RONALD, A.