| 发明名称 |
NITROGENOUS TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES WITH TNF ACTIVITY |
| 摘要 |
The invention concerns a compound of formula (I), wherein: X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; R2 and R3 independently represent a hydrogen atom or a C1-C4 alkyl group; R4 represents a hydrogen atom or a C1-C4 alkyl group; n is 0 or 1; A represents a heterocycle selected among pyridine, pyrimidine, pyrazine and pyridazine optionally mono-or di-substituted by a C1-C4 alkyl or C1-C4 alkoxy group; and their N-oxides and their salts or solvates.
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| 申请公布号 |
WO03044010(A1) |
申请公布日期 |
2003.05.30 |
| 申请号 |
WO2002FR03929 |
申请日期 |
2002.11.18 |
| 申请人 |
SANOFI-SYNTHELABO;BARONI, MARCO;BOURRIE, BERNARD;CASELLAS PIERRE;PULEO, LETIZIA |
发明人 |
BARONI, MARCO;BOURRIE, BERNARD;CASELLAS PIERRE;PULEO, LETIZIA |
| 分类号 |
C07D401/08;A61K31/4545;A61K31/497;A61P1/00;A61P3/10;A61P7/00;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P19/02;A61P19/06;A61P19/10;A61P21/04;A61P25/00;A61P25/04;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P33/02;A61P35/00;A61P37/02;A61P43/00;C07D401/10;C07D401/14;C07D403/08;(IPC1-7):C07D401/10;A61K31/452;A61K31/454 |
主分类号 |
C07D401/08 |
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