发明名称 |
TUMOR SPECIFIC MONOCLONAL ANTIBODIES |
摘要 |
The invention provides tumor-specific human monoclonal antibodies and functional fragments. Also provided are nucleic acids encoding tumor-specific human monoclonal antibodies and functional fragments. A method for reducing neoplastic cell proliferation is also provided. The method consists of administering an effective amount of a tumor-specific human monoclonal antibody or functional fragment. Also provided is a method of detecting a neoplastic cell in a sample. The method consists of contacting a cell with a tumor-specific monoclonal antibody or functional fragment and detecting the specific binding of the human monoclonal antibody or functional fragment to the sample.
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申请公布号 |
WO03044036(A1) |
申请公布日期 |
2003.05.30 |
申请号 |
WO2002US37134 |
申请日期 |
2002.11.19 |
申请人 |
APPLIED MOLECULAR EVOLUTION, INC.;WATKINS, JEFFRY, D. |
发明人 |
WATKINS, JEFFRY, D. |
分类号 |
G01N33/574;A61K39/395;A61P35/00;C07K16/30;C07K16/32;C12N15/09;C12Q1/02;G01N33/577;(IPC1-7):C07H21/04;C07K16/00 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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