SUBSTITUTED BICYCLO[3.3.1]NONAN-2,4,9-TRIONES AS PHARMACEUTICAL ACTIVE INGREDIENTS

摘要

The invention relates to the use of substituted bicyclo[3.3.1]nonan-2,4,9- triones, especially clusianon and clusianon derivatives, as pharmaceutical active ingredients or medicamentous active ingredients, especially for producing medicaments for the prophylactic and/or therapeutic (curative) treatment of tumour or cancer diseases, and of viral diseases. The above- mentioned compounds can be used in cytostatic agents and antiviral agents (virostatic agents). They are especially used as inhibitors of topoisomerase s and telomerases and as regulators during the MAP kinase signal transduction and can thus intervene on a cellular scale in the mechanism for multiplicati on of tumour or cancer cells and viruses.