发明名称 |
COMPOSITION AND METHOD FOR MODULATING BAR/FXR RECEPTOR ACTIVITY |
摘要 |
Methods for modulating the activity of the mammalian BAR/FXR receptor. The methods include methods of treating a hypocholesterolemic mammal comprising contacting the mammal with synthetic compounds able to modulate an activity characteristic of the BAR/FXR receptor. Other methods include a method of treating colon cancer in a mammal comprising administering a compound having a BAR/FXR antagonistic activity. |
申请公布号 |
WO03043581(A2) |
申请公布日期 |
2003.05.30 |
申请号 |
WO2002US37192 |
申请日期 |
2002.11.19 |
申请人 |
ALLERGAN, INC. |
发明人 |
FORMAN, BARRY, M.;BEARD, RICHARD, L.;DUSSAULT, ISABELLE;CHANDRARATNA, ROSHANTHA, A. |
分类号 |
C12N15/09;A61K31/192;A61K31/202;A61K31/203;A61K31/695;A61P3/00;A61P35/00;A61P43/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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