摘要 |
The invention relates to biological arrays, biological microarrays, and methods of using the arrrays and microarrays to detect the amount and/or presence of a biological molecule in a biological sample. Biological arrays of the invention comprise a solidified, sectionable matrix comprising a plurality of wells disposed therein and one or more biological samples disposed within the plurality of wells, which biological arrays optionally comprise an internal standard preparation and/or an orientation marker. Sections or slices of the biological arrays are mounted on a planar substrate surface to form cellular microarrays of the invention. In alternative cellular microarrays of the invention, the matrix material is a temperature-sensitive material removable from the microarray leaving cellular biological material on the substrate surface. |
申请人 |
GENENTECH, INC. |
发明人 |
FRANTZ, GRETCHEN;LANDON, TRENT;PEALE, FRANKLIN, JR., V;PHAM, THINH, QUANG;STEPHAN, JEAN-PHILIPPE, F.;DUNLAP, DEBRA, Y.;HILLAN, KENNETH, J. |