发明名称 |
PROCESS FOR THE MANUFACTURE OF HUMAN MONONUCLEAR PHAGOCYTIC LEUKOCYTES |
摘要 |
A process for the manufacture of human mononuclear phagocytic leukocytes comprises incubating monocytes isolated from a blood sample of an individual and skin segments from the same individual, removing the dermis segments fro m the incubation mixture and sedimenting the obtained activated mononuclear phagocytic leukocytes by centrifugation, washing and resuspending the activated phagocytic leukocytes in the medium, and evaluating the culture fo r its suitability for human administration. Cellular therapy products are made from the obtained cultures and are useful for promoting axonal regeneration in the CNS, wound healing and treatment of myocardial infarction.
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申请公布号 |
CA2467046(A1) |
申请公布日期 |
2003.05.30 |
申请号 |
CA20022467046 |
申请日期 |
2002.11.21 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
ASH, ISSAR;KLEINER BAKIMER, RONIT;FULGA, VALENTIN;EISENBACH-SCHWARTZ, MICHAL |
分类号 |
A61K35/12;A61K35/14;A61K45/00;A61L27/00;A61P3/10;A61P9/10;A61P17/02;A61P25/00;C12N5/02;C12N5/0786;(IPC1-7):C12N5/02;C12N5/06;C12N5/08 |
主分类号 |
A61K35/12 |
代理机构 |
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地址 |
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