发明名称 |
Immunostimulatory nucleic acid molecules for activating dendritic cells |
摘要 |
The present invention relates generally to methods and products for activating dendritic cells. In particular, the invention relates to oligonucleotides which have a specific sequence including at least one unmethylated CpG dinucleotide which are useful for activating dendritic cells. The methods are useful for in vitro, ex-vivo, and in vivo methods such as cancer immunotherapeutics, treatment of infectious disease and treatment of allergic disease. |
申请公布号 |
US2003100527(A1) |
申请公布日期 |
2003.05.29 |
申请号 |
US20020161229 |
申请日期 |
2002.06.03 |
申请人 |
THE UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
KRIEG ARTHUR M.;HARTMANN GUNTHER |
分类号 |
A61K31/00;A61K31/4706;A61K39/39;A61P37/04;C07H21/00;C12N5/0784;C12N5/08;C12Q1/68;(IPC1-7):A61K48/00;C12N15/85 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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