发明名称 Immunostimulatory nucleic acid molecules for activating dendritic cells
摘要 The present invention relates generally to methods and products for activating dendritic cells. In particular, the invention relates to oligonucleotides which have a specific sequence including at least one unmethylated CpG dinucleotide which are useful for activating dendritic cells. The methods are useful for in vitro, ex-vivo, and in vivo methods such as cancer immunotherapeutics, treatment of infectious disease and treatment of allergic disease.
申请公布号 US2003100527(A1) 申请公布日期 2003.05.29
申请号 US20020161229 申请日期 2002.06.03
申请人 THE UNIVERSITY OF IOWA RESEARCH FOUNDATION 发明人 KRIEG ARTHUR M.;HARTMANN GUNTHER
分类号 A61K31/00;A61K31/4706;A61K39/39;A61P37/04;C07H21/00;C12N5/0784;C12N5/08;C12Q1/68;(IPC1-7):A61K48/00;C12N15/85 主分类号 A61K31/00
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