发明名称 |
Fully human antibody Fab fragments with human interferon-gamma neutralizing activity |
摘要 |
Selective binding agents of interferon-gamma (IFNgamma) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to IFNgamma and may be used to prevent or treat conditions relating to autoimmune and inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.
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申请公布号 |
US2003099647(A1) |
申请公布日期 |
2003.05.29 |
申请号 |
US20010972656 |
申请日期 |
2001.10.05 |
申请人 |
DESHPANDE RAJENDRA V.;TSAI MEI-MEI |
发明人 |
DESHPANDE RAJENDRA V.;TSAI MEI-MEI |
分类号 |
C07K16/24;(IPC1-7):A61K39/395 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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