| 摘要 |
Ipaf nucleic acid molecules and encoded polypeptides are provided. Also provided are methods of using Ipaf polypeptides and nucleic acid molecules. The Invention also provides methods of screening for inhibitors or enhancers of Ipaf-mediated apoptosis or procaspase-1 processing. The invention further provides production, isolation and purification of Ipaf polypeptides as well as antibodies against said polypeptides. In addition, the invention provides compositions of Ipaf polypeptides, anti-Ipaf antibodies, and/or Ipaf nucleic acid molecules that can be utilized for diagnostic or therapeutic purposes.
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