发明名称 Integrin receptor inhibitors
摘要 Provided are compounds of formula (I) wherein A, Q, W, X, Y, Z, R1 to R4, m and n are as defined herein. Compounds of the invention bind to alpha4 integrin receptors and thereby inhibit binding of ligands for alpha4 integrins which is useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with alpha4 integrins or their ligands.
申请公布号 US2003100599(A1) 申请公布日期 2003.05.29
申请号 US20020313147 申请日期 2002.12.06
申请人 GENENTECH, INC. 发明人 ARTIS DEAN R.;JACKSON DAVID Y.;RAWSON THOMAS E.;REYNOLDS MARK E.;SUTHERLIN DANIEL P.;STANLEY MARK S.
分类号 A61K31/195;A61K31/403;A61P1/04;A61P1/12;A61P1/16;A61P1/18;A61P3/10;A61P11/00;A61P11/02;A61P11/06;A61P15/14;A61P17/00;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07C233/25;C07C233/60;C07C233/81;C07C237/04;C07C237/20;C07C237/22;C07C237/42;C07D207/16;C07D207/48;C07D209/88;C07D403/12;C07D405/12;(IPC1-7):A61K31/401;A61K31/198;C07C235/84;C0727/22 主分类号 A61K31/195
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