发明名称 |
System for detecting protease |
摘要 |
Disclosed is a system for detecting a protease inside a cell. In one embodiment, the system includes a chimeric protein that comprises as covalently linked components: 1) at least one optionally masked signal protein; 2) at least one protease-specific cleavage site; and 3) at least one detectable amino acid sequence. The invention has a wide spectrum of applications including use in the detection of novel protease inhibitors inside cells and tissue.
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申请公布号 |
US2003100707(A1) |
申请公布日期 |
2003.05.29 |
申请号 |
US20020214932 |
申请日期 |
2002.08.08 |
申请人 |
AHRAM BIOSYSTEMS INC. |
发明人 |
HWANG INHWAN;KIM DAE HEON;LEE YONG JIK |
分类号 |
G01N33/50;C07K19/00;C12N5/10;C12N15/09;C12Q1/02;C12Q1/37;G01N21/76;G01N33/15;(IPC1-7):C07K14/415;C12P21/06;C12P21/02;C12N5/06;C12N5/04 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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