| 发明名称 |
HYDANTOINASE VARIANTS WITH IMPROVED PROPERTIES AND THEIR USE FOR THE PRODUCTION OF AMINO ACIDS |
| 摘要 |
Hydantoinase enzymes are mutants of a previously isolated hydantoinase having the amino acid SEQ. ID. NO. 2. The mutants include amino acids substitutions at positions (95, 154, 180, 251 and/or 255) of the wild type hyndantoinase (SEQ. ID. NO. 2). The mutant hydantoinases, like the parent hydantoinase, are used in the production of optically pure amino acids. |
| 申请公布号 |
EP1165763(A4) |
申请公布日期 |
2003.05.28 |
| 申请号 |
EP20000921477 |
申请日期 |
2000.03.28 |
| 申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY;DEGUSSA AG |
发明人 |
ARNOLD, FRANCES, H.;MAY, OLIVER;DRAUZ, KARLHEINZ;BOMMARIUS, ANDREAS |
| 分类号 |
C12N15/09;C07H21/04;C12N1/15;C12N1/19;C12N1/20;C12N1/21;C12N5/10;C12N9/78;C12N9/86;C12N15/00;C12N15/63;C12N15/70;C12N15/74;C12P13/04;C12P13/06;C12P13/08;C12P13/12;C12P41/00;C12R1/19 |
主分类号 |
C12N15/09 |
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