发明名称 PRE-CONDITIONING AGAINST CELL DEATH
摘要 Apoptosis and/or necrosis related disorders in the mammalian body, namely radiation exposure disorders, chemical exposure and ingestion disorders, neurological disorders and physical trauma disorders, are treated, and their onset is counteracted by pre-conditioning, by extracting from the mammalian body an aliquot of blood, subjecting the extracted aliquot, ex vivo, to an oxidative stressor such as exposure to ozone gas, a temperature stressor, i.e. temperatures above or below body temperatures, and ultraviolet light, and re-injecting the treated blood aliquot into the mammalian body. The treatment has the effect of decreasing apoptosis/necrosis in the body, and of pre-conditioning the body better to withstand subsequently encountered apoptosis-inducing events.
申请公布号 EP1146885(B1) 申请公布日期 2003.05.28
申请号 EP20000900465 申请日期 2000.01.11
申请人 CENTRE DE RECHERCHE DU CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL;VASOGEN IRELAND LIMITED 发明人 HAMET, PAVEL;TREMBLAY, JOHANNE;DESROSIER, CHRISTINE;CHENG, HUIFANG;ARKADY MANDEL;ANTHONY E. BOLTON
分类号 A61K35/14;A61M1/02;A61M1/36;A61P1/16;A61P7/00;A61P13/12;A61P17/02;A61P25/00;A61P25/16;A61P25/28;A61P37/04;A61P39/02;A61P43/00 主分类号 A61K35/14
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