| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivative of homopiperazine of the formula (II) R1, its isotope or its pharmaceutically acceptable salt where R means hydrogen atom, alkyl, cycloalkyl; means aminophenyl, nitrophenyl, hydroxyphenyl, alkoxyphenyl or pyridyl, pyridazyl, pyrazinyl, quinolinyl or isoquinolinyl group. Compounds can be used as ligands of acetylchloine nicotinic receptors in diseases where cholinergic system of central and peripheral nervous system is involved. EFFECT: valuable medicinal properties of compounds. 14 cl, 1 tbl |
