发明名称 QUINOLINYL PIPERIDIN 4 YLIDENE METHYL BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN.
摘要 <p>Compounds of general formula (I), where R1 is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, and triazolyl; where each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1 C6 alkyl, NO2, CF3, C1 C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain.</p>
申请公布号 MXPA02009759(A) 申请公布日期 2003.05.27
申请号 MX2002PA09759 申请日期 2001.03.30
申请人 ASTRAZENECA AB 发明人 BROWN, WILLIAM
分类号 C07D401/14;A61K31/4523;A61K31/4709;A61P1/04;A61P9/12;A61P11/00;A61P13/02;A61P19/02;A61P19/08;A61P23/00;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P37/08;A61P39/02;A61P43/00;C07D211/68;C07D401/06;C07D405/14;C07D409/14 主分类号 C07D401/14
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