PARAMYXOVIRUS VECTOR ENCODING ANGIOGENESIS GENE AND UTILIZATION THEREOF

摘要

A paramyxovirus vector encoding an angiogenesis gene. Use of the paramyxovirus vector makes it possible to efficiently transfer the angiogenesis gene into an individual tissue. FGF2 gene administered in vivo expresses the angiogenesis gene accompanied by no edema in an ischemic tissue, thereby preventing necrosis due to the ischemia. This vector is appropriately usable in gene therapy targeting ischemic tissues.