发明名称 |
Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells |
摘要 |
A G protein-coupled receptor (GPCR) which is activated by oncogenes. The receptor is found predominantly in hematopoietic cells and tissues and functions as a tumor suppressor gene and induces cell cycle arrest. This receptor may play an important role in regulating the proliferation and differentiation of hematopoietic cells. Regulation of receptor activity has several therapeutic applications.
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申请公布号 |
US6569995(B1) |
申请公布日期 |
2003.05.27 |
申请号 |
US20010768670 |
申请日期 |
2001.01.23 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
WENG ZHIGANG;WITTE OWEN N. |
分类号 |
G01N33/50;A61K38/00;A61K39/00;A61K45/00;A61K48/00;A61P35/02;A61P43/00;C07K14/705;C12N15/09;C12N15/12;C12P21/02;G01N33/15;G01N33/53;G01N33/566;G01N33/74;(IPC1-7):C07K16/28;A61K39/395 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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