| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a new effective and safe medicine for treating a diabetic composition. SOLUTION: The pharmaceutical composition includes a new substituted indole alkanol acid (represented by the general formula I) interacting with an aldose reductase and suppressing the aldose reactase. (Wherein, A is a 1-4C alkylene substituted with a 1-2C alkyl or a mono- or di-substituted with a halogen; z is a bond; R1 is H, a 1-6C alkyl or a halogen; R2 , R3 , R4 and R5 are each independently H, a halogen, nitro, a 1-6C alkyl, (substituted) benzyl or the like; R6 is H or a 1-6C alkyl).</p> |
