| 摘要 |
PROBLEM TO BE SOLVED: To provide an immunomodulating agent, a cell adhesion inhibitor and an agent for the treatment and prevention of autoimmune diseases except for rheumatoid arthritis. SOLUTION: A 4H-1-benzopyran-4-one derivative of formula or its salt has excellent immunomodulating action and cell adhesion inhibiting action and is expectable to have an ameliorating effect on the autoimmune diseases except for rheumatoid arthritis comparable to the effect of steroid drugs. Accordingly, the 4H-1-benzopyran-4-one derivative of formula or its salt is useful for the treatment and prevention of autoimmune diseases except for rheumatoid arthritis (such as systemic lupus erythematosus, scleroderma, mixed connective tissue disease, polyarteritis nodosa, multiple myositis/dermatomyositis, Sjoegren's syndrome, Behcet disease, multiple sclerosis, autoimmune diabetes, chronic thyroiditis, psoriasis, primary athyreosis, pernicious anaemia, myasthenia gravis, ulcerative colitis, chronic active hepatitis, autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura).
|
