发明名称 |
Detecting and quantifying analytes, useful e.g. for antibodies or antigens, based on formation of chains of functionalized, colloidal magnetic particles |
摘要 |
Detecting and/or quantifying (M1) at least one analyte (A) in a liquid comprising using colloidal magnetic particles (B), functionalized on the surface with at least one ligand (L) specific for (A), is new. M1 comprises: (a) combining test sample and (B); (b) applying a magnetic field strong enough to structure (B) as chains; (c) maintaining the field for long enough to allow coupling/association of (I) with at least two (L), present on two adjacent particles in the chain; (d) turning of the field; and (e) detecting presence/absence of (I), and optionally its concentration, from the presence/absence of permanent chains of (B). An Independent claim is also included for a reagent kit containing (B).
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申请公布号 |
FR2832507(A1) |
申请公布日期 |
2003.05.23 |
申请号 |
FR20010015011 |
申请日期 |
2001.11.20 |
申请人 |
DIAGNOSTICA STAGO;BIBETTE JEROME |
发明人 |
BIBETTE JEROME MICHEL JACQUES |
分类号 |
G01N33/553;C12N15/09;C12Q1/68;G01N21/78;G01N33/53;G01N33/543;G01N33/566;G01N33/569;(IPC1-7):G01N33/543 |
主分类号 |
G01N33/553 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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