NON-AROMATIC HETEROCYCLIC ESTERS OF FURAN-2-ONE-ESTERS OF 17. BETA.-CARBOXYL OR 17 . BETA. -CARBOTHIO GLUCOCORTICOIDS

摘要

A compound of formula (I), wherein R1 represents O, S or NH; R2 represents a 4-7 membered non-aromatic ring containing 1-3 heteroatoms selected from O, N and S optionally substituted with one or more methyl groups and/or halogen atoms; R3 represents hydrogen, methyl (which may be in either the &agr; or &bgr; configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and --- represents a single or a double bond; and salts and solvates thereof.