发明名称 |
SUSTAINED RELEASE FILM PREPARATION FOR LOCAL ADMINISTRATION COMPRISING PROSTAGLANDIN DERIVATIVE AS ACTIVE INGREDIENT |
摘要 |
A persistent filmy preparation which comprises methyl (11.alpha.,13E,15.alpha.)-9-oxo-11,15-dihydroxy-16-(3-methoxymethylphenyl)- 17,18,19,20-tetranor-5-thiaprost-13-enoate represented by the formula (I): ( I) or a nontoxic salt thereof as an active ingredient and a bioabsorbable polym er as a substrate and which is for use in topical administration to a sick location where the bone amount is small; and a remedy for bone amount reduction which comprises the persistent filmy preparation. The persistent filmy preparation, which contains the compound (I) as an active ingredient, promotes bone formation upon topical administration and is useful for treatments for bone amount reduction.
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申请公布号 |
CA2467061(A1) |
申请公布日期 |
2003.05.22 |
申请号 |
CA20022467061 |
申请日期 |
2002.07.22 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
TABATA, YASUHIKO;NISHIURA, AKIO |
分类号 |
A61K31/5575;A61L24/00;A61L24/04;A61L27/14;A61L27/54;A61L27/58;A61P1/02;A61P3/14;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P35/04;(IPC1-7):A61K31/557;A61K9/70 |
主分类号 |
A61K31/5575 |
代理机构 |
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