Method of surface modifying a medical tubing

摘要

The present invention provides a method of using a medical tubing with a pump for administering measured amounts of a beneficial fluid over time to a patient. The method includes the steps of providing a material selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the ethylene copolymers are obtained by copolymerizing ethylene with a comonomer selected from the group consisting of alkyl olefins, alkyl esters of a carboxylic acid and lower alkene esters of a carboxylic acid, or blends thereof; providing an extruder with an extrusion die; extruding the material into a medical tubing; providing a surface modifier solution; preheating the surface modifier solution to a temperature within the range of 30-95° C.; applying the preheated solution onto the tubing at it exits the extrusion die when the tubing is in a molten state or a semi-molten state; and pumping fluid through the tubing with the pump.