METHODS OF MODULATING TOLL-RELATED RECEPTOR (TRR) SIGNALING

摘要

A method of enhancing antigen presentation, comprising the step of supplying to an antigen presenting cell such as a dendritic cell, or precursor cell, a modulator, preferably an inhibitor, fo Toll-related receptor (TRR) signalling. A method of inhibiting antigen presentation, comprising the step of supplying to an antigen presenting cell such as a dentritic cell, or precursor cell, a modulator, preferably an enhancer of Toll-related receptor (TRR) signalling. The inhibitor or TRR signalling may be a dominant negative mutant of MyD88, for example MyD881pr.