摘要 |
The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of YiiM family members, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of YiiM family members, and compounds and compositions that affect YiiM family members activity. |
申请人 |
STRUCTURAL GENOMIX, INC.;PARK, FRANCES;GAJIWALA, KETAN, S.;BUCHANAN, SEAN, GRANT;SAUDER, J., MICHAEL |
发明人 |
PARK, FRANCES;GAJIWALA, KETAN, S.;BUCHANAN, SEAN, GRANT;SAUDER, J., MICHAEL |