| 摘要 |
<p>A transgenic mouse with overexpression of potassium channel BEC1 which is usable as an efficient tool in screening an antidementia substance or a substance improving learning and memory. An in vivo method of screening an antidementia substance or a substance improving learning and memory with the use of the ability of the mouse to memorize and learn as an indication, and an in vivo method of screening an antianxiety substance with the use of acceleration of anxiety as an indication. A process for producing medicinal compositions against dementia, for improving learning and memory or against anxiety which comprise as the active ingredient a substance inhibiting the activity of the potassium channel concerning learning and memory which can be obtained by the above screening methods.</p> |
