| 摘要 |
PROBLEM TO BE SOLVED: To provide a method and a reagent by which antigen (or antibody) measurement is made to be possible over a wide concentration range, by making appropriate measured values obtainable even when an antigen (or antibody) is contained excessively in an immunoreaction liquid as compared with an antibody (or antigen) bonded to insoluble carrier particles, such as the latex, metallic colloid, etc., by suppressing prozone phenomena. SOLUTION: The method uses a prozone phenomenon repressor for immunoreaction measurement composed of one, two, or more kinds of compounds selected from among sulfate- and sulfonate-based anionic surface active agents, such as alkyl sulfateester-, alkylbenzene sulfonate-, alkylnaphthalene sulfonate-, alkyldiphenylether sulfonate-, polyoxyethylene alkyl sulfateester-, polyoxyethylene alkyl aryl sulfate-, alkane sulphonate-based, and other sulfateester- or sulfonate-based anionic surface active agents. The reagent contains the prozone phenomenon repressor for suppressing the occurrence of prozone phenomena in the course of an immunoreaction.
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